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Image Search Results
Journal: Brain Communications
Article Title: Delta-gamma phase-amplitude coupling as a biomarker of postictal generalized EEG suppression
doi: 10.1093/braincomms/fcaa182
Figure Lengend Snippet: State classification of iEEG recordings using a four-state HMM. ( A ) State classification of an example iEEG trace from Patient 2 (reference electrode—FCz), where S2 is a seizure-like state, and S3 is PGES-like state. ( B ) Comparison of HMM-driven S3 state classification to the visually estimated PGES durations, with the overall correlation of 0.77 ( P = 0.009). ( C ) Histogram of S2 durations, with a gamma function fitted to the data. The shape parameter of the gamma function—alpha—was calculated to be 3.54 (95% CI 1.59–7.89), which is consistent with the average alpha for seizure duration distributions from Suffczynski et al. (2006) of 3.03 and from Bauer et al. (2017) of 2.66. ( D ) Histogram of S3 durations, with gamma function fitted to the data with alpha parameter calculated to be 2.21 (95% CI 1.01–4.82) which is consistent with alpha for PGES duration distributions from Bauer et al. (2017) of 1.54. This can also be compared to alpha value of 1.83 (95% CI 1.04–3.20) obtained from distribution of visually estimated PGES durations (not shown). These shape parameters suggest that the transitions (to and from seizure states) occur not according to Poisson process, but rather that the probability of transition varies with time. For both sections ( C ) and ( D ), n = 11.
Article Snippet: HMM-derived ictal and postictal state duration distributions were also fitted using a
Techniques: Comparison